The Origin of Mifepristone and Misoprostol Abortion Pills

Medical abortion is widely practiced around the world. Medical abortion is an easy way of ending pregnancies between 5 to 12 weeks of gestation using abortion pills.

Medical abortion is widely practiced around the world. Medical abortion is an easy way of ending pregnancies between 5 to 12 weeks of gestation using abortion pills. The abortion pills that are easily available in the global markets today, at very affordable rates are Mifepristone and Misoprostol. The popularity of Mifepristone and Misoprostol tablets online is not just restricted to the U.S.A. but is spread to many other parts of the world as well. 

 

Mifepristone is also known as RU-486. Mifepristone sold under the brand name Mifeprex works as the main pill responsible for stopping the development of the fetus i.e., terminating a pregnancy. The Misoprostol pills that are taken in subsequence help to eject the pregnancy tissues from the body. Hence, both the pills work in combination to end a pregnancy and empty the uterus.

 

Today, one can easily buy Mifepristoneand Misoprostol tablets in a Medical Termination of Pregnancy (MTP) kit or an abortion pill pack. But these easily available pills have a history that dates back to the 1970s. 

 

In this article today, we are going to run through the period from the 1970s to the 2000s and highlight some important dates or events that played key roles in making Mifepristone and Misoprostol pills as popular as they are today.

  • The development of the Misoprostol tablet

 

In the year 1973, the medicine Misoprostol was first developed in the U.S.A. Misoprostol was initially developed to treat peptic ulcers (a sore that develops on the lining of the digestive tract i.e.,esophagus, stomach, or small intestines due to the reaction of stomach acids).

 

But it was noticed that Misoprostol showed major side effects when consumed by pregnant women. This was because Misoprostol falls in the prostaglandin class of medicines that cause a condition called cervical ripening. Cervical ripening means the softening of the cervix muscles and their dilation. Misoprostol was also found responsible for inducing contractions in the uterus.

  • The development of the Mifepristone tablet

 

Mifepristone RU-486 was developed in the year 1980 by the researchers at Roussel-Uclaf (a French pharmaceutical company). It was meant to be taken in combination with Misoprostol tablets to induce an abortion. 

  • Legalization of the pills in the other parts of the world

 

The regimen of Mifepristone and Misoprostol pills was legalized in France in the year 1988. Countries like Great Britain, China, and Sweden too legalized the use of these abortion pills much before the U.S.

 

 

  • Approval in the U.S.

 

In the year 2000, after a lot of roadblocks, the U.S. Food and Drug Administration approved the pills Misoprostol and Mifepristone for sale, for ending early pregnancies. Today, these pills have been in use for over 20 years and have been proved to have a success rate of over 90%, when used under the guidance of a licensed medical instructor.

 

Abortion pills have changed the way young girls and women end their pregnancies for the better. There is a very important need to spread awareness about these pills to promote a safe and healthy abortion.




Stella Lee

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