Mass Spectroscopy's Positive and Negative Modes: The LC-MS/MS Method | NorthEast BioLab

The ESI LC-MS/MS technique generates multipletly charged ions with unaltered analytes under the right instrumental conditions. As previously mentioned, the ESI MS negative mode and the positive ion mode are the two polarity modes available for the LC-MS/MS technique. Positive ion mode charges analytes through protonation, whereas negative ion mode charges through deprotonation. Read more visit here: